TY - JOUR
T1 - Preconditioning stimuli and inadvertent preconditioning
AU - Kloner, Robert A.
AU - Przyklenk, Karin
AU - Whittaker, Peter
AU - Hale, Sharon
PY - 1995/2
Y1 - 1995/2
N2 - R.A. Kloner, K. Przyklenk, P. Whittaker, S. Hale. Preconditioning Stimuli and Inadvertent Preconditioning. Journal of Molecular and Cellular Cardiology (1995) 27, 743-747. There are several factors besides brief episodes of total coronary occlusion which can provide sufficient stress to result in a preconditioning-like effect on the size of a myocardial infarction. Partial coronary artery stenosis, hypoxia, stretch, catecholamines, rapid pacing, and certain pharmacologic therapies may provide preconditioning stimuli. These same factors as well as mechanical complications in which a coronary artery is briefly occluded or stenosed prior to a subsequent coronary occulsion may lead to inadvertent preconditioning and confound the results of experimental cardiology studies.
AB - R.A. Kloner, K. Przyklenk, P. Whittaker, S. Hale. Preconditioning Stimuli and Inadvertent Preconditioning. Journal of Molecular and Cellular Cardiology (1995) 27, 743-747. There are several factors besides brief episodes of total coronary occlusion which can provide sufficient stress to result in a preconditioning-like effect on the size of a myocardial infarction. Partial coronary artery stenosis, hypoxia, stretch, catecholamines, rapid pacing, and certain pharmacologic therapies may provide preconditioning stimuli. These same factors as well as mechanical complications in which a coronary artery is briefly occluded or stenosed prior to a subsequent coronary occulsion may lead to inadvertent preconditioning and confound the results of experimental cardiology studies.
KW - Coronary occlusion
KW - Hypoxia
KW - Ischemia
KW - Preconditioning
UR - http://www.scopus.com/inward/record.url?scp=0028944233&partnerID=8YFLogxK
U2 - 10.1016/0022-2828(95)90079-9
DO - 10.1016/0022-2828(95)90079-9
M3 - Editorial
C2 - 7776379
AN - SCOPUS:0028944233
SN - 0022-2828
VL - 27
SP - 743
EP - 747
JO - Journal of Molecular and Cellular Cardiology
JF - Journal of Molecular and Cellular Cardiology
IS - 2
ER -