Predisposing factors for hep hepatocellular carcinoma in North of Pakistan

Saleem Iqbal, Noor Ul Iman, Humera Khan, Sadeeq Ur Rahman, Abdul Hameed, Adnan Wadud Khan, Tariq Mehr

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Objectives: The main objective of this study was to search for predisposing factors for Hepatocellular Carcinoma (HCC) in North of Pakistan. Material and Method: This study was conducted in medical units of Khyber Teaching Hospital, Peshawar, from July 2007 to February 2009. A total of 100 patients were selected. The main tools for the diagnosis of HCC were ultrasound abdomen, CT scan abdomen, serum alpha-feto protein and liver biopsy. Results: Out of one hundred, 80 patients were males, 72% patients were above the age of 60 years. HCV was present in 74% of our patents, 13 (13%) patients turned out to be HBsAg positive, in 04 patients both HCV & HBV were present, while in the rest of 09 (09%) patients no predisposing cause found. Cirrhosis was present in 80% of patients; the P-Value being 0.538. Serum AFP was raised in 72% of patients. Conclusion: It is concluded that chronic HCV infection is the commonest cause of HCC.

Original languageEnglish
Pages (from-to)63-66
Number of pages4
JournalJournal of Medical Sciences
Issue number1
StatePublished - Jan 2010


  • Hepatocellular carcinoma
  • Predisposing factors for hcc


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