Quantitation of human herpesvirus-6 (HHV-6) DNA in a cord blood transplant recipient with chromosomal integration of HHV-6

D. Kobayashi, K. Kogawa, K. Imai, T. Tanaka, S. Hiroi, H. Satoh, K. Tanaka-Taya, S. Nonoyama

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Chromosomal integration of the human herpesvirus-6 (HHV-6) genome (CIHHV-6) is an important consideration if HHV-6 DNA is detected during the course of transplantation. A 4-year-old girl with refractory anemia with excess blasts type-2 was diagnosed with CIHHV-6 before a cord blood transplantation. HHV-6 DNA was serially quantitated by polymerase chain reaction assay in the transplant period. The possibility of HHV-6 reactivation in a transplant recipient with CIHHV-6 was suspected in our case.

Original languageEnglish
Pages (from-to)650-653
Number of pages4
JournalTransplant Infectious Disease
Volume13
Issue number6
DOIs
StatePublished - Dec 2011
Externally publishedYes

Keywords

  • Chromosomal integration
  • HHV-6 genome
  • HHV-6 reactivation
  • Hematopoietic stem cell transplantation
  • Quantitative PCR assay

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