Glutathione peroxidase activity was measured in 10 areas of perfused adult rat brain with the use of a fluorometric assay coupled to NADPH oxidation. The caudate‐putamen and the substantia nigra had the highest activities. Cortical areas and several nuclear areas had somewhat lower activity. Activity was lowest in a white matter structure (corpus callosum). High activity of glutathione peroxidase may be related to the need to reduce hydrogen peroxide arising in the course of monoamine metabolism.
|Number of pages||2|
|Journal||Journal of Neurochemistry|
|State||Published - Oct 1980|
- Glutathione peroxidase—Hydrogen peroxide—Regional distribution. Brannan T. S. et al. Regional distribution of glutathione peroxidase in the adult rat brain. J. Neurochem.35, 1013–1014 (1980)