Retraction Note: Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer’s disease(BMC Neurosci, (2018), 19, (7), 10.1186/s12868-018-0406-3)

Panchanan Maiti, Leela Paladugu, Gary L. Dunbar

Research output: Contribution to journalComment/debate

Abstract

The Editor has retracted this article at the corresponding author’s request. After publication, concerns were raised regarding similarities in the presented data. Specifically: • In Fig. 6, the PFC 5xFAD + SLCP (2d) and CA15xFAD + Cur (2d) images appear highly similar; • Also in Fig. 6, the CA3 5xFAD + Cur (2d) and 5xFAD + SLCP (2d) appear to originate from thesame sample; • Figure 8a GFAP 5xFAD (top) appears highly similar to Fig. 13a GFAP 5xFAD (bottom) with a brightness adjustment. The authors checked their data and identified additional errors:• In Fig. 11a, the two Iba-1 5xFAD images originated from the same sample; • In Fig. 14a, the two Iba-1 5xFAD images originated from the same sample. The Editor and the authors therefore no longer have confidence in the presented data. All authors agree to this retraction. [1] Maiti, P., Paladugu, L. & Dunbar, G.L. Solid lipid curcumin particles provide greater anti-amyloid, antiinflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer’s disease. BMC Neurosci19, 7 (2018).https://doi.org/10.1186/s12868-018-0406-3.

Original languageEnglish
Article number16
JournalBMC Neuroscience
Volume24
Issue number1
DOIs
StatePublished - Dec 2023

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