Reversible Cerebral Vasoconstriction Syndrome and Sickle Cell Disease: A Case Report

Katherine Regling; Daniel Pomerantz; Sandra Narayanan; Deniz Altinok; Lalitha Sivaswamy; Neena I. Marupudi; Michael U. Callaghan; Alissa Martin

doi:10.1097/MPH.0000000000001683

Reversible Cerebral Vasoconstriction Syndrome and Sickle Cell Disease: A Case Report

Katherine Regling, Daniel Pomerantz, Sandra Narayanan, Deniz Altinok, Lalitha Sivaswamy, Neena I. Marupudi, Michael U. Callaghan, Alissa Martin

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Reversible cerebral vasoconstriction syndrome (RCVS), is rare in the pediatric population and is characterized by severe headaches and other neurologic symptoms. We present a case of RCVS occurring concomitantly with posterior reversible encephalopathy syndrome in an 8-year-old African American child with sickle cell disease (HbSS). Imaging studies including computed tomography, magnetic resonance imaging and cerebral angiography of the brain showed acute hemorrhagic stroke and a beaded appearance of peripheral cerebral vessels. In this report, we focus on the typical features of RCVS and discuss the underlying risk factors that may increase the risk in patients with HbSS disease.

Original language	English
Pages (from-to)	E95-E98
Journal	Journal of Pediatric Hematology/Oncology
Volume	43
Issue number	1
DOIs	https://doi.org/10.1097/MPH.0000000000001683
State	Published - Jan 2021

Keywords

pediatrics
posterior reversible encephalopathy syndrome
reversible cerebral vasoconstriction syndrome
sickle cell disease
stroke

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10.1097/MPH.0000000000001683

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abstract = "Reversible cerebral vasoconstriction syndrome (RCVS), is rare in the pediatric population and is characterized by severe headaches and other neurologic symptoms. We present a case of RCVS occurring concomitantly with posterior reversible encephalopathy syndrome in an 8-year-old African American child with sickle cell disease (HbSS). Imaging studies including computed tomography, magnetic resonance imaging and cerebral angiography of the brain showed acute hemorrhagic stroke and a beaded appearance of peripheral cerebral vessels. In this report, we focus on the typical features of RCVS and discuss the underlying risk factors that may increase the risk in patients with HbSS disease.",

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T1 - Reversible Cerebral Vasoconstriction Syndrome and Sickle Cell Disease

T2 - A Case Report

AU - Regling, Katherine

AU - Pomerantz, Daniel

AU - Narayanan, Sandra

AU - Altinok, Deniz

AU - Sivaswamy, Lalitha

AU - Marupudi, Neena I.

AU - Callaghan, Michael U.

AU - Martin, Alissa

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N2 - Reversible cerebral vasoconstriction syndrome (RCVS), is rare in the pediatric population and is characterized by severe headaches and other neurologic symptoms. We present a case of RCVS occurring concomitantly with posterior reversible encephalopathy syndrome in an 8-year-old African American child with sickle cell disease (HbSS). Imaging studies including computed tomography, magnetic resonance imaging and cerebral angiography of the brain showed acute hemorrhagic stroke and a beaded appearance of peripheral cerebral vessels. In this report, we focus on the typical features of RCVS and discuss the underlying risk factors that may increase the risk in patients with HbSS disease.

AB - Reversible cerebral vasoconstriction syndrome (RCVS), is rare in the pediatric population and is characterized by severe headaches and other neurologic symptoms. We present a case of RCVS occurring concomitantly with posterior reversible encephalopathy syndrome in an 8-year-old African American child with sickle cell disease (HbSS). Imaging studies including computed tomography, magnetic resonance imaging and cerebral angiography of the brain showed acute hemorrhagic stroke and a beaded appearance of peripheral cerebral vessels. In this report, we focus on the typical features of RCVS and discuss the underlying risk factors that may increase the risk in patients with HbSS disease.

KW - pediatrics

KW - posterior reversible encephalopathy syndrome

KW - reversible cerebral vasoconstriction syndrome

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Reversible Cerebral Vasoconstriction Syndrome and Sickle Cell Disease: A Case Report

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