Secondary hypertension in overweight and stage 1 hypertensive children: A midwest pediatric nephrology consortium report

Gaurav Kapur, Maheen Ahmed, Cynthia Pan, Mark Mitsnefes, Myra Chiang, Tej K. Mattoo

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

According to the Fourth Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents, stage 1 hypertension is often primary in origin and associated with overweight. In contrast, stage 2 hypertension is more often secondary in origin and, hence, requires more extensive evaluation according to task force recommendations. The objective of this retrospective study was to evaluate whether the presence of stage 1 hypertension in overweight pediatric patients precludes workup for secondary hypertension (SH). This study included children (5-18 years) with hypertension (defined and staged per task force recommendations) referred to 4 pediatric nephrology centers in the Midwest region. Of the 246 referred patients, 166 patients with primary hypertension (PH) and SH were included for body mass index and hypertension stage analysis. The study revealed no significant differences in the mean age at diagnosis (PH, 13.1±3.1 years; SH, 12.4±3.8 years), distribution of overweight (PH, 89.4% BMI >85th percentile; SH, 80% BMI >85th percentile), and stage 1 (PH, 45%; SH, 40%) or 2 hypertensive (PH,55%; SH, 60%) children between PH vs SH. Overweight and presence of stage 1 hypertension should not preclude evaluation for SH.

Original languageEnglish
Pages (from-to)34-39
Number of pages6
JournalJournal of Clinical Hypertension
Volume12
Issue number1
DOIs
StatePublished - 2010

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