Abstract
Self-immolative aryl phthalate esters were conjugated with cleavable masking groups sensitive to light and hydrogen peroxide. The phthalate linker releases the fluorescent dye 7-hydroxycoumarin upon exposure to light or H2O2, respectively, leading to an increase in fluorescence. The light-sensitive aryl phthalate ester is demonstrated as a pro-fluorophore in cultured S2 cells.
Original language | English |
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Pages (from-to) | 11740-11743 |
Number of pages | 4 |
Journal | Journal of Organic Chemistry |
Volume | 79 |
Issue number | 23 |
DOIs | |
State | Published - Dec 5 2014 |
Externally published | Yes |