Sensing and signalling pathways involved in the adaptive regulation of the SNAT2 amino acid transporter

Harinder S. Hundal, R. Hyde, E. L. Cwiklinski, K. MacAulay, P. M. Taylor

Research output: Contribution to journalArticlepeer-review

Abstract

Nutrient sensing and signalling mechanisms controlling the System A transporter SNAT2 have been assessed. SNAT2 appears to be an amino acid (AA) sensor which exerts autoregulatory control of transcription and, potentially, transporter turnover. An additional sensor for large neutral AA may also control SNAT2 through the JNK pathway.

Original languageEnglish
Pages (from-to)15-16
Number of pages2
JournalActa Biomedica de l'Ateneo Parmense
Volume77
Issue numberSUPPL. 3
StatePublished - 2006

Keywords

  • Amino acid transport
  • MAPK
  • Nutrient sensing

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