Sensing and signalling pathways involved in the adaptive regulation of the SNAT2 amino acid transporter

Harinder S. Hundal; R. Hyde; E. L. Cwiklinski; K. MacAulay; P. M. Taylor

Sensing and signalling pathways involved in the adaptive regulation of the SNAT2 amino acid transporter

Harinder S. Hundal, R. Hyde, E. L. Cwiklinski, K. MacAulay, P. M. Taylor

Research output: Contribution to journal › Article › peer-review

Abstract

Nutrient sensing and signalling mechanisms controlling the System A transporter SNAT2 have been assessed. SNAT2 appears to be an amino acid (AA) sensor which exerts autoregulatory control of transcription and, potentially, transporter turnover. An additional sensor for large neutral AA may also control SNAT2 through the JNK pathway.

Original language	English
Pages (from-to)	15-16
Number of pages	2
Journal	Acta Biomedica de l'Ateneo Parmense
Volume	77
Issue number	SUPPL. 3
State	Published - 2006

Keywords

Amino acid transport
MAPK
Nutrient sensing

Cite this

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title = "Sensing and signalling pathways involved in the adaptive regulation of the SNAT2 amino acid transporter",

abstract = "Nutrient sensing and signalling mechanisms controlling the System A transporter SNAT2 have been assessed. SNAT2 appears to be an amino acid (AA) sensor which exerts autoregulatory control of transcription and, potentially, transporter turnover. An additional sensor for large neutral AA may also control SNAT2 through the JNK pathway.",

keywords = "Amino acid transport, MAPK, Nutrient sensing",

author = "Hundal, {Harinder S.} and R. Hyde and Cwiklinski, {E. L.} and K. MacAulay and Taylor, {P. M.}",

year = "2006",

language = "English",

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TY - JOUR

T1 - Sensing and signalling pathways involved in the adaptive regulation of the SNAT2 amino acid transporter

AU - Hundal, Harinder S.

AU - Hyde, R.

AU - Cwiklinski, E. L.

AU - MacAulay, K.

AU - Taylor, P. M.

PY - 2006

Y1 - 2006

N2 - Nutrient sensing and signalling mechanisms controlling the System A transporter SNAT2 have been assessed. SNAT2 appears to be an amino acid (AA) sensor which exerts autoregulatory control of transcription and, potentially, transporter turnover. An additional sensor for large neutral AA may also control SNAT2 through the JNK pathway.

AB - Nutrient sensing and signalling mechanisms controlling the System A transporter SNAT2 have been assessed. SNAT2 appears to be an amino acid (AA) sensor which exerts autoregulatory control of transcription and, potentially, transporter turnover. An additional sensor for large neutral AA may also control SNAT2 through the JNK pathway.

KW - Amino acid transport

KW - MAPK

KW - Nutrient sensing

UR - http://www.scopus.com/inward/record.url?scp=33845316725&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:33845316725

VL - 77

SP - 15

EP - 16

JO - Acta Biomedica de l'Ateneo Parmense

JF - Acta Biomedica de l'Ateneo Parmense

SN - 0392-4203

IS - SUPPL. 3

ER -

Sensing and signalling pathways involved in the adaptive regulation of the SNAT2 amino acid transporter

Abstract

Keywords

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