Sporadic primary hyperparathyroidism: Medical and surgical updates

Zeina Habib, Adam Kabaker, Pauline Camacho

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


This review discusses recent findings on the clinical presentation, evaluation, medical and surgical management of primary hyperparathyroidism. Medical management includes the use of cinacalcet and bisphosphonates for bone loss and correction of vitamin D deficiency. Surgical updates reviewed recent studies on the preoperative localization of the disease, specifically, sestamibi scans, 4DCT and MRI. Focused parathyroidectomy continues to be the preferred surgical approach for a select group of patients, guided by intraoperative use of PTH and new technology, such as endoscopic and robotic platforms; however, there appears to be no difference in long-term success compared to the traditional approach.

Original languageEnglish
Pages (from-to)31-44
Number of pages14
JournalExpert Review of Endocrinology and Metabolism
Issue number1
StatePublished - Jan 2014


  • bisphosphonates
  • bone loss
  • cinacalcet
  • hypercalcemia
  • normocalcemic primary hyperparathyroidism
  • parathyroidectomy
  • primary hyperparathyroidism
  • vitamin D deficiency


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