Synthesis and evaluation of 17α-20E-21-(4-substituted phenyl)-19-norpregna-1,3,5(10),20-tetraene-3,17β-diols as probes for the estrogen receptor α hormone binding domain

Biochemistry, Genetics and Molecular Biology

• Binding Affinity 60%
• Binding Domain 60%
• Binding Energy 20%
• Estradiol 80%
• Estrogen Receptor 100%
• HBD 40%
• Hormone Binding 60%
• Molecular Dynamics 20%
• Molecular Model 40%
• Position 40%
• Probe 80%
• Receptor Affinity 40%
• Solid 40%
• Solution and Solubility 40%
• Structure Activity Relation 20%
• Synthesis 20%

Neuroscience

• Amino Acids 20%
• Binding Affinity 60%
• Diethylstilbestrol 80%
• Eicosanoid Receptor 20%
• Estradiol Derivative 20%
• Estrogen Receptor 100%
• Hormone Binding 60%
• Ligand 60%
• Protein 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Diethylstilbestrol 80%
• Glycine 20%
• Hormone 60%
• Ligand 60%
• Molecular Modeling 40%
• Palladium 20%
• Protein 20%
• Receptor 60%
• Structure Activity Relationship 20%