Synthesis of clickable amphiphilic polysaccharides as nanoscopic assemblies

Liye Fu, Lingyao Li, Jun Wang, Kyle Knickelbein, Lin Zhang, Ian Milligan, Yi Xu, Kylie O’hara, Lindsay Bitterman, Wenjun Du

Research output: Contribution to journalArticlepeer-review


The synthesis of clickable polysaccharides was achieved by using alkynylated 1,6-anhydro glucopyranose as a monomer and BF3·OEt2 as an effective catalyst. Subsequent click conjugation with polyethylene glycol (PEG) afforded PEG-grafted polysaccharides in nearly quantitative efficiency.

Original languageEnglish
Pages (from-to)12742-12745
Number of pages4
JournalChemical Communications
Issue number84
StatePublished - Sep 25 2014


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