The role of platelet-rich plasma in inguinal wound healing in vascular surgery patients

D. Kirk Lawlor, Guy Derose, Kenneth A. Harris, Marge B. Lovell, Teresa V. Novick, Thomas L. Forbes

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


The objective was to determine whether incision application of platelet-rich plasma (PRP) will decrease postoperative wound complications in vascular surgery patients. A prospective, randomized trial randomized 81 incisions in 51 patients who underwent femoral artery exposure for elective revascularization procedures or endovascular abdominal aneurysm repairs. Incidence of diabetes, chronic renal failure, prosthetic grafts, body mass index (BMI), and steroid use did not differ. Using the ASEPSIS wound classification system, we found no difference in incidence of wound infection. Wound complications occurred in 9 (23%) of 40 of PRP group and 9 (22%) of 41 of non-PRP. Severe wound complications developed in 5 (13%) PRP and 6 (5%) of non-PRP (P = NS). In multivariate analysis, there were no predictors for wound infection. Groin wound complications rates are common in this patient group. Platelet-rich plasma did not decrease the incidence of groin wound complications in our patients

Original languageEnglish
Pages (from-to)241-245
Number of pages5
JournalVascular and Endovascular Surgery
Issue number3
StatePublished - Apr 2011
Externally publishedYes


  • complications
  • platelet rich plasma
  • wound infection


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