Therapeutic Hypothermia: How Can We Optimize This Therapy to Further Improve Outcomes?

Girija Natarajan, Abbot Laptook, Seetha Shankaran

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations

Abstract

Neonatal hypoxic-ischemic encephalopathy remains associated with considerable death and disability. In multiple randomized controlled trials, therapeutic hypothermia for neonatal moderate or severe hypoxic-ischemic encephalopathy among term infants has been shown to be safe and effective in reducing death and disability in survivors. In this article, the current status of infant and childhood outcomes following this therapy is reviewed. The clinical approaches that may help to optimize this innovative neuroprotective therapy are presented.

Original languageEnglish
Pages (from-to)241-255
Number of pages15
JournalClinics in Perinatology
Volume45
Issue number2
DOIs
StatePublished - Jun 2018

Keywords

  • Cooling
  • Hypoxic-ischemic encephalopathy
  • Neonate

Fingerprint

Dive into the research topics of 'Therapeutic Hypothermia: How Can We Optimize This Therapy to Further Improve Outcomes?'. Together they form a unique fingerprint.

Cite this