Three-dimensional ultrasound in the diagnosis of fetal agenesis of corpus callosum

Qiu Ju Wei, Ai Lu Cai, Li Mei Xie, Xiao Guang Wang, Bing Wang, Jun Zhang, Xin Tian Wang

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To explore the value of three-dimensional ultrasound in the diagnosis of fetal agenesis of the corpus callosum (ACC). Methods: Three-dimensional ultrasound (3D US) with tomography ultrasound imaging (TUI) mode was used in 14 fetuses with suspected ACC by two-dimensional ultrasound. The results were compared with that of MRI and 30 normal fetuses. Results: The diagnosis consequence of MRI of 8 fetuses was accord with that of ultrasound in 12 fetuses who were accepted MR examination. The accuracy of prenatal 3D US in the diagnosis of fetal ACC was 66.67% (8/12), sensitivity was 80.00% (8/10), misdiagnosis rate was 20.00% (2/10), positive predictive value was 80.00% (8/10). Conclusion: Successive and multiple sectioned observation can obtain direct and reliable evidences to diagnose fetal ACC with TUI mode of three-dimensional ultrasound without examining time extending. The image of sequential sagittal section of TUI mode of three-dimensional ultrasound is helpful to increase the detection rate of fetal ACC.

Original languageEnglish
Pages (from-to)1663-1667
Number of pages5
JournalChinese Journal of Medical Imaging Technology
Volume27
Issue number8
StatePublished - Aug 2011
Externally publishedYes

Keywords

  • Agenesis of the corpus callosum
  • Fetus
  • Ultrasonography, prenatal

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