Transfusion support to Dengue patients in a hospital based blood transfusion service in north India

Rajendra Chaudhary; Dheeraj Khetan; Seema Sinha; Pratul Sinha; Atul Sonker; Prashant Pandey; Sudipta Sekhar Das; Prashant Agarwal; Vijaylaxmi Ray

doi:10.1016/j.transci.2006.08.007

Transfusion support to Dengue patients in a hospital based blood transfusion service in north India

Rajendra Chaudhary, Dheeraj Khetan, Seema Sinha, Pratul Sinha, Atul Sonker, Prashant Pandey, Sudipta Sekhar Das, Prashant Agarwal, Vijaylaxmi Ray

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42 Scopus citations

Abstract

We evaluated transfusion requirements in a retrospective study of 245 patients with various categories of Dengue infection. The majority (155/245) of our patients were of the Dengue fever (DF) category. There was no correlation between clinical bleed and platelet count as 81 non-bleeding patients were having counts <20 × 10³/μL. Coagulopathy was observed in 37% of the patients with Dengue hemorrhagic fever or Dengue shock syndrome. A rapid response to platelet and fresh frozen plasma (FFP) transfusion was observed in all cases. However, inappropriate transfusion was a major concern as transfusion of 21.5% platelet concentrates was considered inappropriate.

Original language	English
Pages (from-to)	239-244
Number of pages	6
Journal	Transfusion and Apheresis Science
Volume	35
Issue number	3
DOIs	https://doi.org/10.1016/j.transci.2006.08.007
State	Published - Dec 2006
Externally published	Yes

Keywords

Dengue
Thrombocytopenia
Transfusion

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10.1016/j.transci.2006.08.007

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title = "Transfusion support to Dengue patients in a hospital based blood transfusion service in north India",

abstract = "We evaluated transfusion requirements in a retrospective study of 245 patients with various categories of Dengue infection. The majority (155/245) of our patients were of the Dengue fever (DF) category. There was no correlation between clinical bleed and platelet count as 81 non-bleeding patients were having counts <20 × 103/μL. Coagulopathy was observed in 37% of the patients with Dengue hemorrhagic fever or Dengue shock syndrome. A rapid response to platelet and fresh frozen plasma (FFP) transfusion was observed in all cases. However, inappropriate transfusion was a major concern as transfusion of 21.5% platelet concentrates was considered inappropriate.",

keywords = "Dengue, Thrombocytopenia, Transfusion",

author = "Rajendra Chaudhary and Dheeraj Khetan and Seema Sinha and Pratul Sinha and Atul Sonker and Prashant Pandey and Das, {Sudipta Sekhar} and Prashant Agarwal and Vijaylaxmi Ray",

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T1 - Transfusion support to Dengue patients in a hospital based blood transfusion service in north India

AU - Chaudhary, Rajendra

AU - Khetan, Dheeraj

AU - Sinha, Seema

AU - Sinha, Pratul

AU - Sonker, Atul

AU - Pandey, Prashant

AU - Das, Sudipta Sekhar

AU - Agarwal, Prashant

AU - Ray, Vijaylaxmi

PY - 2006/12

Y1 - 2006/12

N2 - We evaluated transfusion requirements in a retrospective study of 245 patients with various categories of Dengue infection. The majority (155/245) of our patients were of the Dengue fever (DF) category. There was no correlation between clinical bleed and platelet count as 81 non-bleeding patients were having counts <20 × 103/μL. Coagulopathy was observed in 37% of the patients with Dengue hemorrhagic fever or Dengue shock syndrome. A rapid response to platelet and fresh frozen plasma (FFP) transfusion was observed in all cases. However, inappropriate transfusion was a major concern as transfusion of 21.5% platelet concentrates was considered inappropriate.

AB - We evaluated transfusion requirements in a retrospective study of 245 patients with various categories of Dengue infection. The majority (155/245) of our patients were of the Dengue fever (DF) category. There was no correlation between clinical bleed and platelet count as 81 non-bleeding patients were having counts <20 × 103/μL. Coagulopathy was observed in 37% of the patients with Dengue hemorrhagic fever or Dengue shock syndrome. A rapid response to platelet and fresh frozen plasma (FFP) transfusion was observed in all cases. However, inappropriate transfusion was a major concern as transfusion of 21.5% platelet concentrates was considered inappropriate.

KW - Dengue

KW - Thrombocytopenia

KW - Transfusion

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Transfusion support to Dengue patients in a hospital based blood transfusion service in north India

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Keywords

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