Trends in hospitalizations and mortality for inflammatory bowel disease from a nationwide database study between 2008 and 2018

Asim Kichloo, Zain El-amir, Dushyant Singh Dahiya, Farah Wani, Hafeez Shaka

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

This study aimed to describe the trends, inpatient outcomes, and disease burden of hospitalizations for ulcerative colitis (UC) and Crohn’s disease (CD). Our study included data on hospitalizations with a principal discharge diagnosis of CD and UC gathered from the Nationwide Inpatient Sample for the years 2008, 2010, 2012, 2014, 2016, and 2018. Individuals ≤18 years and elective hospitalizations were excluded. From 2008 to 2018, we noted a rising trend for UC hospitalizations (P trend < 0.001). However, there was no statistically significant trend for CD hospitalizations (P trend = 0.249). The overall inpatient mortality for UC downtrended from 1.09% in 2008 to 0.42% in 2014 (P trend < 0.001). Additionally, inpatient mortality for CD also downtrended with a decrease from 0.28% in 2008 to 0.17% in 2016 (P trend = 0.002). Odds of inpatient mortality from 2008 to 2018 were significantly higher for UC than for CD. In conclusion, both CD and UC saw a significant decline in mortality over the study period, but UC hospitalizations had a higher odds of inpatient mortality for all study years.

Original languageEnglish
Pages (from-to)550-554
Number of pages5
JournalBaylor University Medical Center Proceedings
Volume34
Issue number5
DOIs
StatePublished - 2021

Keywords

  • Crohn’s disease
  • Nationwide Inpatient Sample
  • hospitalizations
  • mortality
  • trends
  • ulcerative colitis

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